Category: Homeostasis in Immunology

Role of Exosomes in the Regulation of T-Cell Mediated Immune Responses and in Autoimmune Disease

Anel, A., Gallego-Lleyda, A., de Miguel, D., Naval, J., & Martínez-Lostao, L. (2019). Role of exosomes in the regulation of T-cell mediated immune responses and in autoimmune disease. Cells, 8(2), 154. Abstract T-cell mediated immune responses should be regulated to avoid the development of autoimmune or chronic inflammatory diseases. Several mechanisms have been described to regulate this …

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Homeostasis and Self-Tolerance in the Immune System: Turning Lymphocytes off

Van Parijs, L., & Abbas, A. K. (1998). Homeostasis and self-tolerance in the immune system: turning lymphocytes off. Science, 280(5361), 243-248. Abstract The immune system responds in a regulated fashion to microbes and eliminates them, but it does not respond to self-antigens. Several regulatory mechanisms function to terminate responses to foreign antigens, returning the immune system to …

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